What does this research mean for the field?

Modest doses of ethanol alter extramyocardial influences on left ventricular function, such as heart rate, preload, and afterload, but do not impair myocardial contractility in healthy subjects. Novelty: ClaimNovelty.CONTRADICTORY. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

February 1, 1983HeartOpen Access

Acute cardiovascular effects of ethanol A controlled non-invasive study.

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Why the study?

Does acute ethanol ingestion alter left ventricular function or myocardial performance in healthy volunteers?

Population

22 healthy volunteers (11 men and 11 women)

Comparison

Ethanol (1 g/kg orally within 60 minutes) vs Same volume of juice substituted for ethanol

Design

Other

Follow-up

3 hours

Authors

MKMarkku KupariCardiac Imaging

Discussion

Member takes

Implication

Acute ethanol does not impair myocardial performance in healthy subjects; challenges prior views that PEP/ET changes indicate reduced contractility.

Structured PICO

Does acute ethanol ingestion alter left ventricular function or myocardial performance in healthy volunteers?

Population

22 healthy volunteers (11 men and 11 women)

Intervention

Ethanol (1 g/kg orally within 60 minutes)

Comparator

Same volume of juice substituted for ethanol (each subject served as their own control)

Outcome

Acute cardiac effects measured by M-mode echocardiography and systolic time intervals for three hours after beginning ingestionsurrogate

Modest doses of alcohol alter extramyocardial influences on left ventricular function (heart rate, preload, and afterload) but do not impair myocardial performance in healthy subjects.

Cite This Study

Markku Kupari (1983) studied this question.

synapsesocial.com/papers/6a1d3045ba65f5ee325df6fa https://doi.org/10.1136/hrt.49.2.174

Topics

Echocardiography

View Full Paper

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February 1, 1983HeartOpen Access

Acute cardiovascular effects of ethanol A controlled non-invasive study.

View Full Paper

Ask AI

Bookmark

Why the study?

Does acute ethanol ingestion alter left ventricular function or myocardial performance in healthy volunteers?

Population

22 healthy volunteers (11 men and 11 women)

Comparison

Ethanol (1 g/kg orally within 60 minutes) vs Same volume of juice substituted for ethanol

Design

Other

Follow-up

3 hours

Authors

MKMarkku KupariCardiac Imaging

Discussion

Member takes

Implication

Acute ethanol does not impair myocardial performance in healthy subjects; challenges prior views that PEP/ET changes indicate reduced contractility.

Structured PICO

Does acute ethanol ingestion alter left ventricular function or myocardial performance in healthy volunteers?

Population

22 healthy volunteers (11 men and 11 women)

Intervention

Ethanol (1 g/kg orally within 60 minutes)

Comparator

Same volume of juice substituted for ethanol (each subject served as their own control)

Outcome

Acute cardiac effects measured by M-mode echocardiography and systolic time intervals for three hours after beginning ingestionsurrogate

Modest doses of alcohol alter extramyocardial influences on left ventricular function (heart rate, preload, and afterload) but do not impair myocardial performance in healthy subjects.

Cite This Study

Markku Kupari (1983) studied this question.

synapsesocial.com/papers/6a1d3045ba65f5ee325df6fa https://doi.org/10.1136/hrt.49.2.174

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Echocardiography

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