Population
Escherichia coli expressing three capsid proteins of foot-and-mouth disease virus (FMDV)
Design
Preclinical
Authors
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Extends SUMO-based VLP production to FMDV in E. coli; leaves open in vivo efficacy and broader vaccine applications.
A SUMO fusion protein approach in E. coli successfully produced stable virus-like particles of foot-and-mouth disease virus, offering a potential method for producing VLPs of other viruses.
Lee et al. (2009) studied this question.
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