Does bilateral oophorectomy increase the degree of coronary atherosclerosis in women compared to age-matched controls?
Bilateral oophorectomy is associated with an increased degree of coronary atherosclerosis compared to control women, suggesting a protective cardiovascular effect of intact ovarian function.
The degree of coronary atherosclerosis in 49 hearts obtained from bilaterally oophorectomized women was compared with the degree of sclerosis in 600 hearts from women and in 600 hearts from men of comparable ages. On the average the degree of coronary sclerosis in the bilaterally oophorectomized women was greater than in control women but less than in control men.
WUEST et al. (1953) studied this question.
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