Key result
Women aged 45-65 with CAD show more prior MIs, severe occlusions, and risk factors than men.
Why the study?
Do women aged 45-65 years with CAD have a different disease severity and risk factor profile compared to men of the same age?
Observational (n=449)
Yes
Do women aged 45-65 years with CAD have a different disease severity and risk factor profile compared to men of the same age?
Relatively young women (45-65 years) hospitalized with CAD present with more severe coronary disease and a higher burden of cardiovascular risk factors compared to men of the same age.
May warrant closer risk-factor monitoring in midlife women with CAD; leaves open whether sex-specific thresholds improve outcomes.
This retrospective study aimed to characterize coronary artery disease (CAD) and its risk factors among relatively young women, as compared to men in a similar age group. Confirmed cases of CAD were compared regarding their medical background, performance and outcome of coronary artery procedures, physical profile and lifestyle information. The study population included 179 women and 270 men aged 45-65 years who were hospitalized during the study period 1990-1995 in the Hadassah Medical Centers. Significantly more women presented with histories of prior myocardial infarction and a higher number of vessels occluded by 80% or more and required percutaneous transluminal coronary angioplasty for 3 or more arteries, and the women had a higher incidence of risk factors such as diabetes, hypertension and hypercholesterolemia than their male counterparts.
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Hochner‐Celnikier et al. (2002) conducted an observational in Coronary artery disease (CAD) (n=449). Female sex vs. Male sex was evaluated on Extent, severity, and risk factors of CAD. Women aged 45-65 with CAD had significantly more prior myocardial infarctions, severe vessel occlusions, and higher incidences of diabetes, hypertension, and hypercholesterolemia than men.
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