What does this research mean for the field?

The prevalence of secondary hypertension among general outpatient hypertensive patients is 9.1%—higher than previously reported—and can be effectively screened using hormone concentration measurements rather than CT or ultrasound. Novelty: ClaimNovelty.CONTRADICTORY. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

January 1, 2004Hypertension ResearchOpen Access

Prospective Study on the Prevalence of Secondary Hypertension among Hypertensive Patients Visiting a General Outpatient Clinic in Japan

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Why the study?

What is the prevalence of secondary hypertension among hypertensive outpatients, and can a systematic screening protocol identify curable cases?

Structured PICO

What is the prevalence of secondary hypertension among hypertensive outpatients, and can a systematic screening protocol identify curable cases?

Population

1,020 hypertensive patients visiting a general outpatient clinic in Japan

Intervention

Two-step screening protocol for secondary hypertension including initial screening (plasma aldosterone, plasma renin activity, serum cortisol, plasma catecholamine, abdominal ultrasonography) and secondary screening (furosemide plus upright test, captopril renography, dexamethasone suppression test, 24-h urine catecholamine, abdominal CT)

Outcome

Prevalence of secondary hypertension

Systematic hormonal screening reveals a higher than expected prevalence (9.1%) of curable secondary hypertension in a general outpatient setting, highlighting the importance of screening to avoid long-term antihypertensive use.

Discussion

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Implication

Supports broader outpatient screening for curable secondary hypertension; challenges low-prevalence consensus yet remains hypothesis-generating.

Cite This Study

Omura et al. (2004) studied this question.

synapsesocial.com/papers/6a1d3ab25b7fddc3520501e2 https://doi.org/10.1291/hypres.27.193

Topics

Hypertension management

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Implication

Supports broader outpatient screening for curable secondary hypertension; challenges low-prevalence consensus yet remains hypothesis-generating.

Prospective Study on the Prevalence of Secondary Hypertension among Hypertensive Patients Visiting a General Outpatient Clinic in Japan

Structured PICO

Discussion

Implication

Cite This Study

Topics

Prospective Study on the Prevalence of Secondary Hypertension among Hypertensive Patients Visiting a General Outpatient Clinic in Japan

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider