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This study investigates the behavior of adiponectin in relation to injured vascular walls.

An Adipocyte-Derived Plasma Protein, Adiponectin, Adheres to Injured Vascular Walls

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This study investigates the behavior of adiponectin in relation to injured vascular walls.
Analyzed adiponectin characteristics in vitro and in vivo
Used solid-phase binding assays to evaluate specific binding to collagen types
Performed immunohistochemical analysis on catheter-injured vessels
Adiponectin was secreted into the medium when cDNA was transfected and detected in human plasma
Specifically bound to collagen types I, III, and V in solid-phase binding assays
Detected in walls of catheter-injured vessels but absent in intact vascular walls

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Randomized trial analyzes adiponectin's binding to vascular walls in response to injury, suggesting its role in vascular repair.

Okamoto et al. (2000) studied this question.

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