Why the study?
The authors sought to assess whether new mapping and ablation technologies can improve success and safety during transvenous radiofrequency transcatheter ablation of epicardial posterior-septal accessory pathways via the coronary sinus in children.
Does transvenous radiofrequency transcatheter ablation using 3D mapping improve outcomes in children with epicardial posterior-septal accessory pathways?
Does transvenous radiofrequency transcatheter ablation using 3D mapping improve outcomes in children with epicardial posterior-septal accessory pathways?
Transvenous radiofrequency ablation of epicardial posterior-septal accessory pathways in children achieves definitive elimination in over half of cases, with contact-force catheters potentially reducing recurrences.
Answers are grounded in this paper and cite their sources.
Supports feasibility of transvenous ablation for pediatric epicardial pathways; leaves open questions on recurrence reduction and optimal techniques in larger prospective studies.
INTRODUCTION: The aim of the study was to revise our more recent experience about epicardial posterior-septal accessory pathways radiofrequency transcatheter ablation in children and young patients using a transvenous approach through the coronary sinus, to understand if new mapping and ablation technologies can increase success rate and safety. METHODS AND RESULTS: Twenty children (mean age 13 ± 3 years) with epicardial posterior-septal accessory pathways (14 in coronary sinus and 6 in the middle cardiac vein) underwent radiofrequency transcatheter ablation with CARTO-3® system with help of the CARTO-Univu® module. Acute success rate was 73%. No patient was lost to follow-up (mean time 11.4 ± 9 months). The recurrence rate was 19%. Two patients underwent a successful redo-procedure; the overall long-term success rate was 65%. Navistar® catheter presented the highest acute success rate in the coronary sinus. Navistar SmartTouch® was the only catheter that did not present recurrences after the acute success, and it was successfully used in two patients previously unsuccessfully treated with a Navistar ThermoCool®. Acute success rate was 79% without image integration with angio-CT, while it was 63% after the introduction of CARTO-Merge®. CONCLUSION: Epicardial posterior-septal accessory pathways can be definitively eliminated by transvenous radiofrequency transcatheter ablation in more than half of the cases in children. Acute success rate does not seem to depend on catheters used, but contact-force catheter seems to be useful in cases with recurrences. Image integration with cardiac-CT does not increase success rate, but it is useful to detect coronary sinus alterations to better guide ablation strategy.
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Drago et al. (2021) studied this question.
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