Key result
Thrombolytic therapy in elderly patients (>70 years) with acute STEMI was associated with an in-hospital mortality rate of 30.2% and an intracranial hemorrhage rate of 0.9%.
Why the study?
Many large, randomized trials have excluded patients over 70 years old, leaving the benefits and complications of thrombolytic therapy in elderly patients with STEMI unclear.
What are the in-hospital outcomes and complication rates of thrombolytic therapy in elderly patients (>70 years) with acute STEMI?
Population
106 elderly patients (age >70 years) with acute STEMI receiving thrombolytic therapy
Design
Single-center observational study
Follow-up
Index hospitalization
Authors
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High associated mortality warrants caution with thrombolysis in elderly STEMI when PCI unavailable; leaves open need for randomized comparisons.
Observational (n=106)
No
What are the in-hospital outcomes and complication rates of thrombolytic therapy in elderly patients (>70 years) with acute STEMI?
Thrombolytic therapy in elderly STEMI patients (>70 years) is associated with a high in-hospital mortality (30.2%) and complication rate, though it remains a necessary option when primary PCI is not feasible.
Thakkar et al. (2022) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=106). Thrombolytic therapy was evaluated on In-hospital mortality. Thrombolytic therapy in elderly patients (>70 years) with acute STEMI was associated with an in-hospital mortality rate of 30.2% and an intracranial hemorrhage rate of 0.9%.
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