Polyacrylamide model fluids were evaluated for their viscoelastic properties to serve as non-Newtonian blood analogs for in vitro heart valve testing.
May aid in vitro heart valve testing; leaves open validation in clinical or human blood contexts.
New heart valves and other cardiovascular assist systems have to be tested for hydrodynamic performance. In place of human blood simple model fluids like glycerol solutions are employed often due to ethical and practical reasons. But blood exhibits complex non-Newtonian and viscoelastic behaviour. Rheological blood properties are reviewed based on literature and own experimental results. Furthermore we studied polymer solutions with respect to blood-like flow behaviour. Rheology was assessed by means of the low shear rotational viscometer (LS 40, Mettler-Toledo, Switzerland) under stationary and dynamic shear conditions (variation of frequency and angular displacement).
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Lerche et al. (1993) studied this question.
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