Key result
Lower body mass index was independently associated with an increased risk of adverse in-hospital outcomes, particularly left ventricular failure, following percutaneous coronary intervention (OR 0.95).
Why the study?
Does lower BMI (<23 kg/m2) increase the risk of in-hospital left ventricular failure in patients undergoing percutaneous coronary intervention?
Cross-Sectional (n=100)
No
Does lower BMI (<23 kg/m2) increase the risk of in-hospital left ventricular failure in patients undergoing percutaneous coronary intervention?
Lower BMI (<23 kg/m2) is associated with a higher risk of in-hospital left ventricular failure following PCI compared to normal or high BMI, supporting the existence of an obesity paradox.
Should not yet inform BMI-based PCI risk models; hypothesis-generating for obesity paradox requiring prospective validation.
Background: Obesity is an independent cardiovascular risk factor. The most common anthropometric measurement used to quantify obesity is body mass index (BMI). Percutaneous coronary intervention (PCI) is associated with various types of complications. The relationship between BMI and in-hospital complications particularly left ventricular failure (LVF) after PCI has not been thoroughly investigated, especially in Bangladesh.Methods: This cross sectional observational study was conducted at National Institute of Cardiovascular Diseases, on total 100 patients who underwent PCI with two equally divided groups on the basis of BMI of Asian ethnicity: Group I (BMI < 23 kg/m2) and Group II (BMI e” 23.0 kg/m2). In-hospital LVF after PCI were observed and recorded.Results: The mean BMI of study population was 23.9 ± 1.9 kg/m2. The sum of occurrence of adverse in-hospital outcomes was 14.0%. Complications were significantly (p < 0.01) higher in Group I than Group II. Among all adverse in-hospital outcomes, only acute left ventricular failure was found to be statistically significant between groups (p < 0.01). The difference of mean duration of hospital stay after PCI was higher in Group-I which was statistically significant (p < 0.01). Diabetes mellitus and dyslipidemia were found to be the independent predictors for developing adverse inhospital outcome (OR= 1.68 and 1.46; 95% CI = 1.25 – 2.24 and 1.16 – 1.83; p = 0.018 and 0.040, respectively). BMI was inversely associated with in-hospital outcomes after PCI (OR = 0.95; 95% CI = 0.91 – 0.98; p = 0.007).Conclusion: BMI is inversely associated with in-hospital LVF after PCI. The underweight and normal weight people are at greater risk to experience in-hospital LVF than overweight and obese people following PCI.
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Siddiqui et al. (2018) conducted a cross-sectional in Patients undergoing percutaneous coronary intervention (PCI) (n=100). BMI < 23 kg/m2 (Underweight/Normal) vs. BMI ≥ 23.0 kg/m2 (Overweight/Obese) was evaluated on Adverse in-hospital outcomes (OR 0.95, 95% CI 0.91-0.98, p=0.007). Lower body mass index was independently associated with an increased risk of adverse in-hospital outcomes, particularly left ventricular failure, following percutaneous coronary intervention (OR 0.95).
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