Key result
Well-controlled type 2 diabetes is not linked to impaired VO2max or exercise kinetics vs controls.
Why the study?
Does well-controlled uncomplicated type 2 diabetes impair maximal oxygen uptake or slow VO2 and HR kinetics in obese sedentary men compared to matched controls?
Cross-Sectional (n=13)
No
Does well-controlled uncomplicated type 2 diabetes impair maximal oxygen uptake or slow VO2 and HR kinetics in obese sedentary men compared to matched controls?
Absolute Event Rate: 27.8% vs 27.5%
p-value: p=0.95
Well-controlled uncomplicated type 2 diabetes in obese sedentary men is not associated with a reduction in VO2 max or slower VO2 and HR kinetics during exercise.
May not impair VO2max or kinetics in well-controlled T2D; leaves open effects across glycemic control or activity levels.
The aim of this study was to examine the impact of well-controlled uncomplicated type 2 diabetes (T2D) on exercise performance. Six obese sedentary men with T2D and 7 control participants without diabetes matched for age, sex and body mass index were recruited. Anthropometric characteristics, blood samples, resting cardiac and pulmonary functions and maximal oxygen uptake (VO 2 max) and ventilatory threshold were measured on a first visit. On the four subsequent visits, participants performed step transitions (6 min) of moderate-intensity exercise on an upright cycle ergometer from unloaded pedaling to 80 % of ventilatory threshold. VO 2 (τVO 2 ) and HR (τHR) kinetics were characterized with a mono-exponential model. VO 2 max (27.8±4.0 vs. 27.5±5.3 ml kg -1 min -1 ; p=0.95), τVO 2 (43±6 vs. 43±10 s; p=0.73) and τHR (42±17 vs. 43±13 s; p=0.94) were similar between diabetics and controls respectively. The remaining variables were also similar between groups. These results suggest that well-controlled T2D is not associated with a reduction in VO 2 max or slower τVO 2 and τHR.
No takes yet. Share an insight, caveat, or question.
Caron et al. (2016) conducted a cross-sectional in Type 2 diabetes (n=13). Type 2 diabetes vs. Participants without diabetes was evaluated on Maximal oxygen uptake (VO2max) (p=0.95). Well-controlled uncomplicated type 2 diabetes in obese sedentary men was not associated with a reduction in maximal oxygen uptake or slower oxygen uptake and heart rate kinetics compared to matched controls.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: