Key result
The High-Density Grid mapping catheter was safe in pediatric and CHD patients, with lower acute success (93.2% vs 99.4%; p=0.01) likely reflecting bias toward its use in more complex arrhythmias.
Why the study?
The safety and utility of the Advisor High-Density Grid mapping catheter in children and congenital heart disease patients were not well described.
Is the High-Density Grid mapping catheter safe and effective in pediatric and congenital heart disease patients undergoing ablation?
Cohort (n=261)
No
Is the High-Density Grid mapping catheter safe and effective in pediatric and congenital heart disease patients undergoing ablation?
The High-Density Grid mapping catheter is safe for use in pediatric and congenital heart disease patients, with lower success rates likely reflecting its preferential use in more complex arrhythmias.
Answers are grounded in this paper and cite their sources.
HDGC appears safe for pediatric/CHD ablations; observational data leaves open comparative efficacy amid selection bias.
INTRODUCTION: The safety and utility of the Advisor™ High-Density Grid mapping catheter (HDGC) in children and congenital heart disease (CHD) patients are not well described. METHODS: A single-center retrospective cohort study of pediatric and CHD patients undergoing electrophysiology study and ablation to determine the effect of HDGC use on outcomes including complications, fluoroscopy use, procedure duration, acute ablation success, and arrhythmia recurrence. RESULTS: HDGC was used in 74/261 (28.3%) cases. HDGC subjects differed by median age (17 vs. 13 years; p < 0.001), weight (68 vs. 50 kg; p < 0.001), and prevalence of significant CHD (42% vs. 3%; p < 0.001). Arrhythmia substrates were dissimilar: HGDC cases had higher frequencies of intra-atrial re-entrant tachycardia (25.7% vs. 0.5%), atrial flutter (8.1% vs. 1.1%), ectopic atrial tachycardia (13.5% vs. 3.7%), and premature ventricular contractions (9.5% vs. 0.5%), and lower incidences of atrioventricular re-entrant tachycardia (16.2% vs. 46.1%). Complications were rare (n = 5, 1.9%) with no significant difference between groups (p = 1.00). Procedure duration-but not fluoroscopy exposure-was significantly longer in HDGC cases (median 256 vs. 216 min, p < 0.001). Acute success was lower (93.2% vs. 99.4%; p = 0.01) and recurrences higher (13.2% vs. 3.8%; p = 0.016) in HDGC compared to non-HDGC cases. CONCLUSION: HDGC use in children and CHD patients is safe and not associated with higher complication rates. The lower acute success and higher recurrence rates in HDGC cases likely reflect a bias toward HDGC use in more complex arrhythmia substrates rather than less favorable ablation outcomes.
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Newlon et al. (2022) conducted a cohort in Pediatric and complex congenital heart disease arrhythmias (n=261). Advisor High-Density Grid mapping catheter (HDGC) vs. Non-HDGC mapping was evaluated on Acute ablation success (p=0.01). The High-Density Grid mapping catheter was safe in pediatric and CHD patients, with lower acute success (93.2% vs 99.4%; p=0.01) likely reflecting bias toward its use in more complex arrhythmias.
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