Key result
Transcatheter aortic valve replacement was preferred by 79.5% of patients with aortic stenosis over surgical replacement, as they were willing to tolerate clinical risks for reduced invasiveness.
Why the study?
Choosing between SAVR and TAVR requires patients to trade off benefits and risks, creating a need to evaluate which outcomes patients consider important and quantify their preferences.
Do patients with aortic stenosis prefer the attribute profile of TAVR over SAVR when weighing benefits and risks?
Cross-Sectional (n=219)
Do patients with aortic stenosis prefer the attribute profile of TAVR over SAVR when weighing benefits and risks?
Most patients with aortic stenosis are willing to tolerate sizable increases in clinical risk in exchange for the reduced invasiveness of TAVR, resulting in a strong preference for TAVR over SAVR.
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May inform shared decision-making for aortic stenosis; leaves open whether preferences predict real-world outcomes.
Marsh et al. (2020) conducted a cross-sectional in Aortic stenosis (n=219). Transcatheter aortic valve replacement (TAVR) vs. Surgical aortic valve replacement (SAVR) was evaluated on Patient preference for TAVR vs SAVR (Monte Carlo Simulation). Transcatheter aortic valve replacement was preferred by 79.5% of patients with aortic stenosis over surgical replacement, as they were willing to tolerate clinical risks for reduced invasiveness.