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July 1, 1996Journal of Biological ChemistryOpen Access

The CED-3/ICE-like Protease Mch2 Is Activated during Apoptosis and Cleaves the Death Substrate Lamin A

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Authors

KOKim OrthThe University of Texas Southwestern Medical Center
Arul M. Chinnaiyan
Arul M. ChinnaiyanBuffalo State UniversityMGManish GargBLK Super Speciality Hospital

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Cite This Study

Orth et al. (1996) studied this question.

synapsesocial.com/papers/6a1d85d533e2df9c962fa64dhttps://doi.org/10.1074/jbc.271.28.16443
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme.1994 · 595 citations
  2. 2Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition.1996 · 292 citations
  3. 3Identification and Characterization of ICH-2, a Novel Member of the Interleukin-1β-converting Enzyme Family of Cysteine Proteases1995 · 263 citations
  4. 4Identification and Characterization of CPP32/Mch2 Homolog 1, a Novel Cysteine Protease Similar to CPP321996 · 225 citations
  5. 5Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution.1995 · 516 citations