Key result
Computed tomography pulmonary arteriography identified pulmonary embolism in 5% of pregnant women and potential alternative causes for symptoms in 12% of those without embolism.
Why the study?
What is the frequency of nonthromboembolic imaging abnormalities in pregnant women referred for CTPA?
Observational (n=100)
What is the frequency of nonthromboembolic imaging abnormalities in pregnant women referred for CTPA?
In pregnant women referred for CTPA, pulmonary embolism is found in 5%, while alternative diagnoses explaining symptoms are found in 12% of those without PE.
CTPA may reveal treatable alternatives in symptomatic pregnant women; leaves open whether routine use improves outcomes.
PURPOSE: The study sought to determine the frequency of nonthromboembolic imaging abnormalities in pregnant women referred for computed tomography pulmonary arteriography (CTPA). MATERIALS AND METHODS: CTPA studies on 100 consecutive pregnant women performed over a 5-year period were reviewed independently by 2 radiologists, with conflicts resolved by consensus. Age range was 18-43 years (mean 28 years). The presence or absence of pulmonary embolism and of nonthromboembolic imaging abnormalities was recorded. These were graded as A if the abnormalities were thought to provide potential alternative explanations for acute symptoms, B if findings were incidental that required clinical or radiologic follow-up, and C if the findings did not require further action. RESULTS: Pulmonary embolism was seen in 5 women. In 2 of these additional findings of consolidation and infarction were seen. Ninety-five women did not have pulmonary embolism. Eleven women (12%) had grade A abnormalities; 6 cases of consolidation, 2 cases of lobar collapse, and 3 cases of heart failure with pleural effusions. One woman had a grade B abnormality due to the presence of pulmonary nodules. Ten women had incidental grade C abnormalities. CONCLUSION: Pulmonary embolism occurs in 5% of pregnant women referred for CTPA. In pregnant women without embolism on CTPA, potential alternative causes for patient symptoms are seen on CT in 12% of cases.
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Moriarty et al. (2015) conducted an observational in Suspected pulmonary embolism in pregnancy (n=100). Computed tomography pulmonary arteriography (CTPA) was evaluated on Frequency of pulmonary embolism and nonthromboembolic imaging abnormalities. Computed tomography pulmonary arteriography identified pulmonary embolism in 5% of pregnant women and potential alternative causes for symptoms in 12% of those without embolism.
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