Why the study?
Does thoracic epidural analgesia combined with fentanyl alter haemodynamic parameters in male patients <65 years old undergoing aortocoronary bypass surgery?
Population
30 male patients < 65 years old with ejection fraction > 0.5 undergoing aortocoronary bypass surgery
Comparison
Thoracic epidural analgesia with bupivacaine… vs High-dose fentanyl (55 mcg/kg) anaesthesia alone
Design
RCT, randomized into 3 groups
Follow-up
20 hours postoperatively
Authors
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May increase vasopressor needs during bypass with TEA in CABG; extends RCT data on regional vs opioid haemodynamics.
Does thoracic epidural analgesia combined with fentanyl alter haemodynamic parameters in male patients <65 years old undergoing aortocoronary bypass surgery?
Thoracic epidural analgesia combined with low-dose fentanyl during CABG lowers systemic vascular resistance and mean arterial pressure during bypass compared to high-dose fentanyl alone, but requires more vasopressor support.
Stenseth et al. (1994) studied this question.
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