Why the study?
Does high thoracic epidural anesthesia attenuate the sympathetic stress response and myocardial oxygen demand in patients undergoing CABG?
Population
20 patients undergoing coronary artery bypass grafting (CABG)
Comparison
High thoracic epidural anesthesia as an adjunct… vs Standardized fentanyl-nitrous oxide anesthesia…
Design
Cohort
Follow-up
Perioperative (pre-bypass period)
Authors
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TEA may blunt sympathetic activation during CABG sternotomy; leaves open outcome benefits and safety in randomized trials.
Does high thoracic epidural anesthesia attenuate the sympathetic stress response and myocardial oxygen demand in patients undergoing CABG?
Thoracic epidural anesthesia during CABG attenuates the surgically mediated sympathetic stress response to sternotomy, preventing increased myocardial oxygen demand without compromising myocardial perfusion.
Kirn et al. (1996) studied this question.
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