Why the study?
Does high thoracic epidural anesthesia increase coronary artery luminal diameter and improve myocardial blood flow in patients with severe coronary artery disease?
Population
36 patients with severe coronary artery disease, divided into two groups.
Comparison
High thoracic epidural anesthesia. vs Baseline (control situation prior to TEA).
Design
Cohort
Authors
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May support TEA for refractory angina via stenotic dilation; hypothesis-generating and requires randomized confirmation before practice change.
Does high thoracic epidural anesthesia increase coronary artery luminal diameter and improve myocardial blood flow in patients with severe coronary artery disease?
High thoracic epidural anesthesia increases the diameter of stenotic epicardial coronary arteries without dilating coronary arterioles, providing a physiological basis for its use in treating severe ischemic chest pain at rest.
Blomberg et al. (1990) studied this question.
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