Why the study?
Does aminophylline improve hemodynamics compared to sodium nitroprusside in patients with refractory heart failure?
Does aminophylline improve hemodynamics compared to sodium nitroprusside in patients with refractory heart failure?
Aminophylline provides no beneficial hemodynamic effects 1 hour post-infusion in refractory heart failure, in contrast to the distinct benefits observed with sodium nitroprusside.
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No hemodynamic benefit with aminophylline at 60-90 min in refractory HF; challenges prior reports yet leaves open need for randomized confirmation.
DiBianco et al. (1980) studied this question.
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