Key result
Real-time free-breathing cardiac MRI using through-time radial GRAPPA showed no clinically significant difference compared to standard breath-hold imaging, with a mean difference in LVEF of -2%.
Why the study?
Does real-time free-breathing cardiac MRI using through-time radial GRAPPA provide comparable left ventricular volumetric measurements to traditional breath-hold ECG-gated MRI in patients and volunteers?
Observational (n=31)
Does real-time free-breathing cardiac MRI using through-time radial GRAPPA provide comparable left ventricular volumetric measurements to traditional breath-hold ECG-gated MRI in patients and volunteers?
Real-time free-breathing cardiac MRI using through-time radial GRAPPA yields left ventricular volumetric measurements comparable to standard breath-hold techniques, providing a viable alternative for patients unable to hold their breath or with arrhythmias.
Cardiac MRI requires a steady cardiac rhythm for ECGgating, and multiple breath-holds to minimize respiratory artifacts. By employing a non-Cartesian parallel imaging in form of through-time radial GRAPPA [1], accelerated imaging can be performed with temporal resolutions of < 50 ms, obviating the need for gating or breath-holding. breath-holding. We tested the hypothesis that volumetric measurements in the LV obtained with the real-time method could replace traditional measurements.
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Nadig et al. (2013) conducted an observational in Left ventricular ejection fraction quantification (n=31). Through-time radial GRAPPA for real-time imaging vs. Standard breath-hold cine imaging was evaluated on Agreement in left ventricular ejection fraction (LVEF) (Mean difference -2%). Real-time free-breathing cardiac MRI using through-time radial GRAPPA showed no clinically significant difference compared to standard breath-hold imaging, with a mean difference in LVEF of -2%.
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