Key result
Real-time cardiac MR imaging accurately quantified LV volumes compared to conventional gradient-echo cine imaging with a mean difference of -0.8 +/- 10.6 ml.
Why the study?
Does real-time cardiac MR imaging accurately quantify LV volumes compared to conventional gradient-echo cine imaging in healthy volunteers?
Observational (n=10)
Does real-time cardiac MR imaging accurately quantify LV volumes compared to conventional gradient-echo cine imaging in healthy volunteers?
Effect estimate: Mean difference -0.8 +/- 10.6 ml
Real-time cardiac MRI provides accurate LV volume quantification comparable to conventional cine imaging, offering a faster alternative for functional cardiac assessment.
Real-time cardiac MR may enable faster LV assessment in volunteers; leaves open validation in patients before clinical use.
The application of real-time magnetic resonance imaging (MRI) techniques to cardiac imaging is particularly attractive because current MR examinations of left ventricular (LV) function can be prohibitively long and are dependent on electrocardiographic triggering. We conducted a study of the minimum spatial and temporal resolution requirements necessary for real-time ventricular function MR imaging to quantify LV volumes accurately, both at resting conditions and during cardiac stress tests. In addition, we implemented a real-time segmented echoplanar imaging pulse sequence and used it to quantify LV volume in 10 healthy volunteers. We compared these results with those obtained using conventional gradient-echo cine imaging and found good agreement throughout the cardiac cycle (mean difference -0.8 +/- 10.6 ml). In conclusion, real-time cardiac MR imaging can be used to quantify LV volumes accurately throughout the cardiac cycle, over the physiologic range of heart rates, thereby decreasing the time required for a complete functional cardiac examination. J. Magn. Reson. Imaging 2000;12:430-438.
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Setser et al. (2000) conducted an observational in Healthy volunteers (n=10). Real-time segmented echoplanar imaging pulse sequence vs. Conventional gradient-echo cine imaging was evaluated on Left ventricular volume quantification (Mean difference -0.8 +/- 10.6 ml). Real-time cardiac MR imaging accurately quantified LV volumes compared to conventional gradient-echo cine imaging with a mean difference of -0.8 +/- 10.6 ml.
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