Why the study?
Does computer-assisted insulin delivery improve glycemic control in type I unstable diabetic patients?
Does computer-assisted insulin delivery improve glycemic control in type I unstable diabetic patients?
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Computer-assisted insulin delivery may provide short-term improvements in HbA1 levels in unstable type I diabetics without increasing hypoglycemia, though long-term benefits remain uncertain.
The aim of the study was to evaluate the effect of a computer-assisted insulin delivery on the glycemic control of type I unstable diabetic patients. 6 subjects, who already received 2-4 daily insulin injections, were treated with a pocket-size microprocessor device for periods lasting 2-14 months. The total daily insulin doses remained unchanged during the experimental period. However, the percentage of regular insulin decreased significantly from 63 +/- 3% to 47 +/- 7% (p less than 0.05). HbA1 levels decreased from 10.1 +/- 0.6% to 9.4 +/- 0.4% after 2 months computer (p less than 0.05). However, in the 2 patients who used the device for 11-14 months, the overall glycemic control was comparable during the basal and experimental periods. Hypoglycemic episodes were not increased.
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Buysschaert et al. (1989) studied this question.
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