Key result
Preclinical rat studies indicate that regular physical exercise increases resting vagal tone, whereas chronic stress and negative psychosocial factors are associated with vagal withdrawal.
This review summarizes preclinical rat studies on the impact of stress, psychosocial factors, and exercise on vagal modulation of resting heart rate and its neurobiological mechanisms.
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Hypothesis-generating for human vagal interventions; extends rat data but requires clinical trials before practice change.
Carnevali et al. (2014) conducted a review in Stress, psychosocial factors, and physical exercise effects on resting heart rate. Preclinical rat studies indicate that regular physical exercise increases resting vagal tone, whereas chronic stress and negative psychosocial factors are associated with vagal withdrawal.
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