Key result
Cine delayed-enhancement MR imaging correctly depicted wall motion in 71% and scar extent in 76% of myocardial segments, with no scarring missed in any patient.
Why the study?
Does a cine delayed-enhancement (DE) pulse sequence accurately depict wall motion and myocardial scar extent during a single acquisition in patients undergoing cardiac MRI?
Observational (n=26)
Does a cine delayed-enhancement (DE) pulse sequence accurately depict wall motion and myocardial scar extent during a single acquisition in patients undergoing cardiac MRI?
Cine delayed-enhancement MR imaging is a promising technique for the simultaneous visualization of wall motion and myocardial scar extent in a single acquisition.
Supports feasibility of single-acquisition cine DE-MRI for wall motion and scar; leaves open prospective validation before clinical adoption.
This study was performed by using an institutional review board-approved protocol, with waived informed consent and HIPAA compliance. The purpose of this study was to preliminarily evaluate a cine delayed-enhancement (DE) pulse sequence for depiction of wall motion and myocardial scar extent during a single acquisition. The technique is based on inversion-recovery single-shot balanced steady-state free precession magnetic resonance imaging. Cine DE images were acquired in 26 patients (18 men, eight women; age range, 25-84 years; mean age, 61 years+/-13 [standard deviation]). Image contrast was consistent throughout each series. Overall (ie, with both readers' scores averaged), the cine DE imaging-depicted wall motion was scored correctly in 71% of myocardial segments. Scar extent was scored correctly in 76% of segments; in no patient was scarring missed. Cine DE imaging is a promising technique for simultaneous visualization of wall motion and myocardial scar extent.
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Setser et al. (2006) conducted an observational in Myocardial scar and wall motion evaluation (n=26). Cine delayed-enhancement (DE) magnetic resonance imaging was evaluated on Depiction of wall motion and myocardial scar extent. Cine delayed-enhancement MR imaging correctly depicted wall motion in 71% and scar extent in 76% of myocardial segments, with no scarring missed in any patient.
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