Viability Assessment With Global Left Ventricular Longitudinal Strain Predicts Recovery of Left Ventricular Function After Acute Myocardial Infarction
Key result
A baseline automated function imaging global LV strain cutoff of -13.7% predicted left ventricular functional recovery at 1 year with 86% sensitivity and 74% specificity.
Why the study?
Does global left ventricular longitudinal strain assessed with automated function imaging early after acute myocardial infarction predict recovery of left ventricular function?
Population
147 patients admitted for acute myocardial infarction, mean age 61+/-11 years
Design
Cohort
Follow-up
1-year
Authors
Discussion
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Member takes
Implication
May support post-MI risk stratification with automated strain; leaves open whether it improves outcomes or guides therapy.
Study Design
Type
Cohort (n=147)
Structured PICO
Does global left ventricular longitudinal strain assessed with automated function imaging early after acute myocardial infarction predict recovery of left ventricular function?
P
Population
147 patients admitted for acute myocardial infarction, mean age 61+/-11 years
I
Intervention
Global left ventricular longitudinal strain assessed with automated function imaging (AFI) via 2D echocardiography within 48 hours of admission
O
Outcome
Recovery of left ventricular function (absolute improvement in LV ejection fraction >= 5%) at 1-year follow-upsurrogate
Main Result
p-value: p=<0.0001
Global left ventricular longitudinal strain assessed by automated function imaging early after acute myocardial infarction is a strong predictor of left ventricular functional recovery at 1 year.
Cite This Study
Mollema et al. (2009) conducted a cohort in Acute myocardial infarction (n=147). Automated function imaging (AFI) global LV strain was evaluated on Absolute improvement in LV ejection fraction ≥5% at 1-year follow-up (p=<0.0001). A baseline automated function imaging global LV strain cutoff of -13.7% predicted left ventricular functional recovery at 1 year with 86% sensitivity and 74% specificity.