Key result
Above 20 kg/m2, each 2 kg/m2 higher BMI was associated with 12% higher IHD mortality (95% CI 6-19%, P=0.0001), whereas below 20 kg/m2 the association appeared reversed.
Why the study?
How is body mass index associated with mortality from ischaemic heart disease in a lean population of adult men?
Population
222,000 Chinese men aged 40-79 from a population-based prospective cohort study.
Design
Cohort
Follow-up
10 years
Authors
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Supports J-shaped BMI-IHD mortality link in lean Chinese men; hypothesis-generating and should not yet change practice.
Cohort (n=222,000)
How is body mass index associated with mortality from ischaemic heart disease in a lean population of adult men?
Effect estimate: 12% higher risk per 2 kg/m2 increase (95% CI 6-19)
p-value: p=0.0001
In a lean population of Chinese men, the relationship between BMI and IHD mortality is J-shaped, with risk increasing above 20 kg/m2 and also increasing at very low BMI levels.
Chen et al. (2005) conducted a cohort in Ischaemic heart disease (n=222,000). Body mass index vs. Different BMI categories was evaluated on Death from IHD (12% higher risk per 2 kg/m2 increase, 95% CI 6-19, p=0.0001). Above 20 kg/m2, each 2 kg/m2 higher BMI was associated with 12% higher IHD mortality (95% CI 6-19%, P=0.0001), whereas below 20 kg/m2 the association appeared reversed.
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