What does this research mean for the field?

Obesity-related hypertension is driven by a combination of increased sympathetic nervous system activity, altered renal sodium handling, and increased adipose tissue expression of the ANP clearance receptor (NPr-C) which blunts the protective effects of natriuretic peptides. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

March 1, 2001Journal of the Renin-Angiotensin-Aldosterone SystemOpen Access

The renin-angiotensin system in obesity hypertension

View Full Paper

Ask AI

Bookmark

Population

Obese individuals with hypertension and animal models of obesity

Design

Review

Authors

ASArya M. SharmaPreventive Cardiology SEStefan EngeliUniversitätsmedizin Greifswald

Discussion

Member takes

Implication

Informs mechanistic research on obesity hypertension; hypothesis-generating without supporting practice changes.

Structured PICO

Population

Obese individuals with hypertension and animal models of obesity

The review highlights the complex interplay of sympathetic overactivity, the renin-angiotensin-aldosterone system, and altered natriuretic peptide clearance in the pathogenesis of obesity-related hypertension.

Cite This Study

Sharma et al. (2001) studied this question.

synapsesocial.com/papers/6a1dd7cad10dad54e1ef60f4 https://doi.org/10.1177/14703203010020012001

View Full Paper

Ask AI

Bookmark

The renin-angiotensin system in obesity hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The renin-angiotensin system in obesity hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider