Can polymerase chain reaction identify Tropheryma whippelii as a causative organism in infective endocarditis?
This report provides the first evidence of Tropheryma whippelii as a causative organism in infective endocarditis using PCR amplification from a native aortic valve.
This report concerns a patient with cardiac manifestation of Whipple's disease. For the first time, the gene that encodes the 16s rRNA of Tropheryma whippelii was identified in a native aortic valve by means of a polymerase chain reaction technique. DNA amplification gives evidence of Tropheryma whippelii as a causative organism in infective endocarditis.
Wendler et al. (Wed,) studied this question.