Key result
Warmer nadir cryoballoon temperatures of -41°C are linked to early pulmonary vein reconduction.
Why the study?
Do balloon temperature and time to pulmonary vein isolation predict early pulmonary vein reconduction and mid-term AF recurrence in patients undergoing cryoballoon ablation?
Population
130 consecutive patients undergoing cryoballoon ablation (CBA) for atrial fibrillation (AF)
Comparison
Cryoballoon ablation with touch-up ablation of… vs Patients and pulmonary veins with versus without…
Design
Cohort
Follow-up
13.4 months
Authors
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Balloon temperature and time to isolation may predict early reconduction after cryoballoon ablation; hypothesis-generating and should not yet change practice.
Observational (n=130)
No
Do balloon temperature and time to pulmonary vein isolation predict early pulmonary vein reconduction and mid-term AF recurrence in patients undergoing cryoballoon ablation?
Absolute Event Rate: -41% vs -49%
p-value: p=<0.0001
Cryoballoon temperature and time to PVI predict early pulmonary vein reconduction, and touch-up ablation of these sites yields high mid-term success rates comparable to patients without early reconduction.
Watanabe et al. (2018) conducted an observational in Atrial fibrillation (n=130). Balloon temperature and time to pulmonary vein isolation vs. Pulmonary veins without early reconduction was evaluated on Nadir balloon temperature in pulmonary veins with early pulmonary vein reconduction (EPVR) versus those without (p=<0.0001). Higher cryoballoon temperatures at the nadir point (-41°C vs -49°C) and longer times to pulmonary vein isolation (90 vs 52 seconds) were significantly associated with early pulmonary vein reconduction.