What does this research mean for the field?

Arterial stiffening associated with aging increases carotid flow augmentation, which explains increasing flow fluctuations in cerebral blood vessels and suggests that the carotid flow augmentation index (FAI) could serve as a marker for cerebral microvascular damage risk. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 1, 2006StrokeOpen Access

Age-Related Changes in Carotid Artery Flow and Pressure Pulses

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Population

56 healthy subjects aged 20 to 72 years

Design

Cross-sectional

Authors

KHKozo HirataKobe Women's University TYToshio YaginumaJichi Medical University MOMichael F. O’RourkeManitoba Health

Discussion

Member takes

Implication

FAI may mark cerebral microvascular damage risk with aging; hypothesis-generating and requires prospective validation before clinical use.

Structured PICO

Population

56 healthy subjects aged 20 to 72 years

Outcome

Relation between the pulsatile components of pressure and flow waveforms in the carotid artery and their change with agesurrogate

Arterial stiffening with aging increases carotid flow augmentation, suggesting that flow augmentation index could serve as a marker for cerebral microvascular damage risk.

Cite This Study

Hirata et al. (2006) studied this question.

synapsesocial.com/papers/6a1ddfdcd10dad54e1ef6641 https://doi.org/10.1161/01.str.0000242289.20381.f4

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Implication

FAI may mark cerebral microvascular damage risk with aging; hypothesis-generating and requires prospective validation before clinical use.

Age-Related Changes in Carotid Artery Flow and Pressure Pulses

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Age-Related Changes in Carotid Artery Flow and Pressure Pulses

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider