What does this research mean for the field?

Q: What does this research mean for the field?

The extent of CT-angiographic collateralization and successful reperfusion are independent predictors of final infarct volume in acute anterior circulation ischemic stroke treated with intra-arterial thrombolysis, whereas time to treatment and initial stroke severity are not. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 4, 2010Cerebrovascular Diseases

CT-Angiographic Collateralization Predicts Final Infarct Volume after Intra-Arterial Thrombolysis for Acute Anterior Circulation Ischemic Stroke

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Why the study?

Does CT-angiographic collateralization predict final infarct volume in patients with acute anterior circulation ischemic stroke treated with intra-arterial thrombolysis?

Population

25 patients with acute middle cerebral and terminal internal carotid artery ischemic stroke undergoing…

Design

Cohort

Follow-up

5 days

Authors

AAAnselm AngermaierUniversitätsmedizin Greifswald SLSönke LangnerUniversitätsmedizin Greifswald MKMichael KirschUniversitätsmedizin Greifswald

Discussion

Member takes

Implication

CTA collateral score may refine infarct volume prognostication after IAT; extends observational data but leaves prospective validation open.

Structured PICO

Does CT-angiographic collateralization predict final infarct volume in patients with acute anterior circulation ischemic stroke treated with intra-arterial thrombolysis?

Population

25 patients (17 women, 8 men, mean age 67.6 ± 12.4 years) with acute middle cerebral and terminal internal carotid artery (MCA/ICA) ischemic stroke undergoing intra-arterial thrombolysis within 6 h after symptom onset.

Intervention

CT angiography collateralization score (CTA-cs) assessment

Outcome

Final infarct volume on CT 5 days after the interventionsurrogate

CT-angiographic collateralization and reperfusion success are independent predictors of final infarct volume in acute MCA/ICA stroke treated with intra-arterial thrombolysis.

Cite This Study

Angermaier et al. (2010) studied this question.

synapsesocial.com/papers/6a1dfbf48b32c80b5460440b https://doi.org/10.1159/000321868

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Implication

CTA collateral score may refine infarct volume prognostication after IAT; extends observational data but leaves prospective validation open.

CT-Angiographic Collateralization Predicts Final Infarct Volume after Intra-Arterial Thrombolysis for Acute Anterior Circulation Ischemic Stroke

Discussion

Member takes

Implication

Structured PICO

Cite This Study

CT-Angiographic Collateralization Predicts Final Infarct Volume after Intra-Arterial Thrombolysis for Acute Anterior Circulation Ischemic Stroke

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider