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January 1, 2007Annals of Noninvasive ElectrocardiologyOpen Access

Slow Delayed Rectifier Potassium Current (IKs) and the Repolarization Reserve

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Authors

NJNorbert JostUniversity of SzegedJPJulius Gy. PappElectrophysiologyAVAndrás VarróElectrophysiology

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Implication

May inform arrhythmia risk assessment when repolarization reserve is impaired; leaves open whether IKs-targeted therapies improve outcomes.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Jost et al. (2007) studied this question.

synapsesocial.com/papers/6a1e01fb348274ea529fbe63https://doi.org/10.1111/j.1542-474x.2007.00140.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1IK of rabbit ventricle is composed of two currents: evidence for IKs1996 · 132 citations
  2. 2Cellular Basis for Complex T Waves and Arrhythmic Activity Following Combined IKr and IKs Block2001 · 131 citations
  3. 3Pharmacology of cardiac potassium channels2004 · 469 citations
  4. 4HMR 1556, A Potent and Selective Blocker of Slowly Activating Delayed Rectifier Potassium Current2003 · 91 citations
  5. 5Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes1998 · 227 citations