Why the study?
Does anticoagulation with heparin and warfarin resolve left ventricular thrombus in a patient with acute myocardial infarction?
Does anticoagulation with heparin and warfarin resolve left ventricular thrombus in a patient with acute myocardial infarction?
This case highlights the clinical utility of echocardiography in diagnosing and monitoring LV thrombus in AMI patients, demonstrating successful resolution with heparin and warfarin therapy.
Case of resolved post-MI LV thrombus on anticoagulation; hypothesis-generating and should not change practice.
Despite the well documented benefit of echocardiography in acute coronary syndromes, its wide-scale use in the Caribbean is limited by access, health literacy and affordability. Because of the limited use of echocardiography in the region, routine complications of acute myocardial infarction (AMI) are not fully appreciated and may go unrecognized, further contributing to increased cardiovascular morbidity and mortality. It is therefore necessary to bring focus to this common clinical condition and highlight the clinical utility of echocardiography in facilitating timely and accurate diagnosis. We report here a case of large left ventricular (LV) thrombus in a patient with AMI. Coronary angiography showed completely occluded left anterior descending artery (LAD) with angiographically normal remaining vessels. Immediate anticoagulation was commenced with heparin and overlapped with warfarin. No Primary Angioplasty (PA) was done based on the evidence from occluded artery trial. LV thrombus was completely resolved on echocardiography at three months. No evidence of thrombo-embolism was found during the resolution of LV thrombus.
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Potu et al. (2012) studied this question.
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