Key result
Immediate anticoagulation with heparin and warfarin led to complete resolution of a large left ventricular thrombus at three months without thrombo-embolism in a patient with AMI.
Case Report (n=1)
Highlights the clinical utility of echocardiography in facilitating timely diagnosis and management of LV thrombus complicating AMI in resource-limited settings.
Supports anticoagulation for post-AMI LV thrombus in select cases; hypothesis-generating and leaves open need for randomized trials.
Despite the well documented benefit of echocardiography in acute coronary syndromes, its wide-scale use in the Caribbean is limited by access, health literacy and affordability. Because of the limited use of echocardiography in the region, routine complications of acute myocardial infarction (AMI) are not fully appreciated and may go unrecognized, further contributing to increased cardiovascular morbidity and mortality. It is therefore necessary to bring focus to this common clinical condition and highlight the clinical utility of echocardiography in facilitating timely and accurate diagnosis. We report here a case of large left ventricular (LV) thrombus in a patient with AMI. Coronary angiography showed completely occluded left anterior descending artery (LAD) with angiographically normal remaining vessels. Immediate anticoagulation was commenced with heparin and overlapped with warfarin. No Primary Angioplasty (PA) was done based on the evidence from occluded artery trial. LV thrombus was completely resolved on echocardiography at three months. No evidence of thrombo-embolism was found during the resolution of LV thrombus.
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Potu et al. (2012) conducted a case report in Acute myocardial infarction with left ventricular thrombus (n=1). Heparin overlapped with warfarin was evaluated on Resolution of LV thrombus. Immediate anticoagulation with heparin and warfarin led to complete resolution of a large left ventricular thrombus at three months without thrombo-embolism in a patient with AMI.
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