What does this research mean for the field?

TAVI patients aged 80 years and older achieve similar long-term survival to the age-matched general population, and those aged 65 and older have comparable quality of life, although overall TAVI survival remains worse due to lower relative survival in younger patients. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

May 22, 2020IJC Heart & VasculatureOpen Access

Survival and quality of life after transcatheter aortic valve implantation relative to the general population

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Why the study?

Survival and quality of life in patients treated by TAVI compared to an age- and sex-matched general population were not well known.

Does survival and quality of life in patients treated with TAVI compare favorably to the age- and sex-matched general population?

Population

5489 TAVI patients from the Netherlands Heart Registration (period 2013-2017)

Comparison

TAVI patients vs Dutch age- and sex-matched general population

Design

Registry-based cohort study

Follow-up

5 years

Authors

JZJo M. ZelisRadboud University Nijmegen MVMarcel van ’t VeerInterventional Cardiology SHSaskia HoutermanCardiac Surgery

Discussion

Member takes

Implication

Supports TAVI matching general-population survival in octogenarians; leaves open randomized confirmation versus medical therapy.

Structured PICO

Does survival and quality of life in patients treated with TAVI compare favorably to the age- and sex-matched general population?

Population

5,489 patients treated by transcatheter aortic valve implantation (TAVI) from the Netherlands Heart Registration (NHR) cohort (period 2013-2017)

Intervention

Transcatheter aortic valve implantation (TAVI)

Comparator

Age- and sex-matched general population from the Netherlands (Statistics Netherlands)

Outcome

Long-term survival and quality of life (QoL)hard clinical

TAVI restores survival and quality of life to levels comparable to the general population in patients aged 80 years and older.

Cite This Study

Zelis et al. (2020) studied this question.

synapsesocial.com/papers/6a1e33ea60864841a668a040 https://doi.org/10.1016/j.ijcha.2020.100536

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Survival and quality of life after transcatheter aortic valve implantation relative to the general population

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Survival and quality of life after transcatheter aortic valve implantation relative to the general population

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider