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April 24, 2021CJC OpenOpen Access

Patients alive at 1 year reported a mean improvement of 24.1 (95% CI, 22.7-25.6) points in the KCCQ-OS at 30 days, which was sustained at 1 year (25.3; 95% CI, 23.8, 26.8).

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Why the study?

Documentation of QOL after TAVI is a Canadian Cardiovascular Society quality indicator, but national results had not been reported.

Does transcatheter aortic valve implantation improve quality of life in a real-world population?

Population

1706 TAVI patients, irrespective of surgical risk, from the British Columbia TAVI Registry

Design

Observational cohort study

Follow-up

1 year

Authors

SLSandra LauckMYMaggie YuLDLillian Ding

Discussion

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Member takes

Overview

Supports sustained QoL gains after TAVI in unselected patients; extends trial data to real-world cohorts but leaves practice implications open.

Structured PICO

Does transcatheter aortic valve implantation improve quality of life in a real-world population?

P
Population
1,706 patients undergoing transcatheter aortic valve implantation (TAVI), irrespective of surgical risk, median age 83 years, 43.5% female, from the British Columbia TAVI Registry.
I
Intervention
Transcatheter aortic valve implantation (TAVI)
O
Outcome
Quality of life measured by the Kansas City Cardiomyopathy Questionnaire overall score (KCCQ-OS) at 30 days and 1 yearpatient reported

TAVI is associated with significant and sustained improvements in quality of life at 30 days and 1 year in a real-world, unselected patient population.

Cite This Study

Lauck et al. (2021) studied this question.

synapsesocial.com/papers/6a1bf3fd27b545b111a94027https://doi.org/10.1016/j.cjco.2021.04.006
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Quality of life in patients with transcatheter aortic valve implantation: an analysis from the INTERVENT project2023 · 7 citations
  2. 2Factors influencing quality-of-life improvement following transcatheter aortic valve implantation: insights from a prospective study with mixed-effects analysis2025 · 7 citations
  3. 3Twelve-Month Quality of Life Improvement and All-Cause Mortality in Elderly Patients Undergoing Transcatheter Aortic Valve Replacement2016 · 17 citations
  4. 4Quality of life improvement is maintained up to two years after transcatheter aortic valve implantation in high-risk surgical candidates2012 · 25 citations
  5. 5Short- and intermediate-term improvement of patient quality of life after transcatheter aortic valve implantation: a single-centre study2014 · 34 citations