August 1, 2012EuroIntervention
Transcatheter aortic valve implantation significantly improved quality of life at two years, with mean SF36-physical scores increasing from 31.9 to 51.5 (p<0.0001).
Why the study?
Does TAVI improve long-term quality of life in high-risk surgical candidates?
Population
100 consecutive high-risk surgical candidates undergoing TAVI with at least two years' follow-up. Mean log…
Comparison
Transcatheter aortic valve implantation using… vs Preoperative baseline
Design
Cohort
Follow-up
2 years
Key result
Transcatheter aortic valve implantation significantly improved quality of life at two years, with mean SF36-physical scores increasing from 31.9 to 51.5 (p<0.0001).
Authors
Discussion
Loading...
Member takes
Overview
Supports TAVI for sustained QoL gains in high-risk patients; extends observational data but leaves open need for randomized confirmation.
Study Design
Type
Cohort (n=100)
Multicenter
No
Structured PICO
Does TAVI improve long-term quality of life in high-risk surgical candidates?
P
Population
100 consecutive high-risk surgical candidates (mean age 79.7 years, 46% female) undergoing TAVI, evaluated for quality of life changes up to two years post-procedure.
E
Exposure
Transcatheter aortic valve implantation (TAVI) using Edwards SAPIEN (n=67) or CoreValve (n=33)
C
Comparator
Preoperative baseline (before-and-after comparison)
O
Outcome
Changes in quality of life (QoL) at two years' follow-up, evaluated with the 36-item short-form health survey (SF-36v2) and the Minnesota Living with Heart Failure Questionnaires (MLHFQ)patient reported
Main Result
Absolute Event Rate: 51.5% vs 31.9%
p-value: p=<0.0001
TAVI in high-risk surgical candidates provides significant and sustained improvements in physical and mental quality of life up to two years post-procedure.
Cite This Study
Taramasso et al. (2012) conducted a cohort in High-risk surgical candidates undergoing TAVI (n=100). Transcatheter aortic valve implantation (TAVI) vs. Preoperative baseline was evaluated on Quality of life (SF36-physical score) (p=<0.0001). Transcatheter aortic valve implantation significantly improved quality of life at two years, with mean SF36-physical scores increasing from 31.9 to 51.5 (p<0.0001).