Why the study?
Does TAVI improve health-related quality of life in elderly patients with severe symptomatic aortic stenosis?
Population
10 studies pooling 1359 elderly patients with severe symptomatic aortic stenosis at high surgical risk
Comparison
Transcatheter aortic valve implantation (TAVI) vs Baseline (preprocedural) status
Design
Meta-analysis
Follow-up
12 to 24 months
Key result
Transcatheter aortic valve implantation significantly improved quality of life in older patients with severe aortic stenosis at 1 year (SF-12 physical score WMD -10.61; 95% CI -15.06 to -6.15).
Authors
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Supports TAVI to enhance 1-year QoL in high-risk elderly severe AS; reinforces Level 1 meta-analytic evidence for its use.
Meta-Analysis (n=1,359)
Does TAVI improve health-related quality of life in elderly patients with severe symptomatic aortic stenosis?
Mean Difference: -10.61 (95% CI -15.06–-6.15)
TAVI provides significant long-term improvements in health-related quality of life for elderly patients with severe symptomatic aortic stenosis at high surgical risk.
Li et al. (2015) conducted a meta-analysis in Severe aortic stenosis (n=1,359). Transcatheter aortic valve implantation (TAVI) vs. Baseline was evaluated on 12-item Short Form (SF-12) physical score at 1 year (WMD -10.61, 95% CI -15.06, -6.15). Transcatheter aortic valve implantation significantly improved quality of life in older patients with severe aortic stenosis at 1 year (SF-12 physical score WMD -10.61; 95% CI -15.06 to -6.15).
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