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September 7, 2012Biomedical PapersOpen Access

General health median significantly improved in TAVI patients (from 50 to 67; P=0.001) with a positive trend in SAVR patients (P=0.060).

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Why the study?

Does TAVI improve quality of life compared to SAVR in high-risk elderly patients with symptomatic severe aortic stenosis?

Population

45 consecutive high-risk patients with symptomatic severe aortic stenosis, average age 82.0 years, logistic…

Comparison

Transcatheter aortic valve implantation… vs Surgical aortic valve replacement with the…

Design

Cohort

Follow-up

360 days

Authors

PKPetr KalaMTMartin TřetinaMPMartin Poloczek

Discussion

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Overview

TAVI linked to QoL gains in high-risk elderly; leaves open superiority versus SAVR pending randomized data.

Structured PICO

Does TAVI improve quality of life compared to SAVR in high-risk elderly patients with symptomatic severe aortic stenosis?

P
Population
45 consecutive high-risk patients with symptomatic severe aortic stenosis, average age 82.0 years, logistic Euroscore 22.3%
I
Intervention
Transcatheter aortic valve implantation (TAVI) transfemoral or transapical using the Edwards-Sapien valve (n=30)
C
Comparator
Surgical aortic valve replacement (SAVR) with the Edwards Perimount bioprosthesis (n=15)
O
Outcome
Quality of life assessed using the standardized EQ-5D questionnaire at 360 dayspatient reported

In high-risk elderly patients with severe aortic stenosis, TAVI significantly improves general quality of life at one year.

Cite This Study

Kala et al. (2012) studied this question.

synapsesocial.com/papers/6a9590177007bd2ef4e3cc8dhttps://doi.org/10.5507/bp.2012.062
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