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September 10, 2025Journal of Cardiovascular Medicine

Factors influencing quality-of-life improvement following transcatheter aortic valve implantation: insights from a prospective study with mixed-effects analysis

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Authors

CRCrina-Ioana RadulescuMAMarianna AdamoACAngelica Cersosimo

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Overview

Prospective analysis identifies comorbidities impacting quality of life post-transcatheter aortic valve implantation, suggesting follow-up implications.

Key Points

  • Transcatheter aortic valve implantation significantly improves quality of life in severe aortic stenosis patients.
  • Mean MLHFQ score improved from 41.1 to 23.4 at 12 months post-procedure, indicating enhanced quality of life.
  • Mixed-effects modeling assessed longitudinal quality of life changes and identified predictors of worse outcomes.
  • Identifying risk factors like peripheral artery disease and paravalvular leak may guide personalized follow-up strategies.

Cite This Study

Radulescu et al. (2025) studied this question.

synapsesocial.com/papers/68c19f7f54b1d3bfb60dac09https://doi.org/10.2459/jcm.0000000000001760
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Quality-of-Life Outcomes After Transcatheter Aortic Valve Implantation in a “Real World” Population: Insights From a Prospective Canadian Database2021 · 24 citations
  2. 2Quality of life in patients with transcatheter aortic valve implantation: an analysis from the INTERVENT project2023 · 7 citations
  3. 3Quality-of-life in elderly patients one year after transcatheter aortic valve implantation for severe aortic stenosis2011 · 55 citations
  4. 4Health-Related Quality of Life After Transcatheter or Surgical Aortic Valve Replacement in High-Risk Patients With Severe Aortic Stenosis2012 · 296 citations
  5. 5Paravalvular Leak After Transcatheter Aortic Valve Implantation Its Incidence, Diagnosis, Clinical Implications, Prevention, Management, and Future Perspectives: A Review Article2021 · 93 citations