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This review assesses how antibiotic treatment for syphilis, chlamydia, and gonorrhoea in pregnant women impacts various birth outcomes.

The impact of antibiotic treatment for syphilis, chlamydia, and gonorrhoea during pregnancy on birth outcomes: A systematic review and meta-analysis

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Systematic review reveals important benefits of antibiotic treatment for syphilis during pregnancy, indicating potential for improved birth outcomes.

This review assesses how antibiotic treatment for syphilis, chlamydia, and gonorrhoea in pregnant women impacts various birth outcomes.
Systematic review and meta-analysis of studies until May 23, 2022.
Search conducted across multiple databases including PubMed and Cochrane.
Focused on non-randomized studies regarding treatment and birth outcomes.
Treatment for syphilis reduced preterm birth by 52% (95% CI = 42%-61%; 11,043 participants), low quality evidence.
Treatment for syphilis reduced stillbirth by 79% (95% CI = 65%-88%; 14,667 participants), low quality evidence.
Chlamydia treatment might reduce low birth weight by 40% (95% CI = 0%-64%; 4,684 participants), low quality evidence.

Tong et al. (2023) studied this question.

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Systematic review reveals important benefits of antibiotic treatment for syphilis during pregnancy, indicating potential for improved birth outcomes.