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April 1, 2010European Journal of Cardio-Thoracic SurgeryOpen Access

The Ross operation — a feasible and safe option in the setting of a bicuspid aortic valve?

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Why the study?

Does the presence of a bicuspid aortic valve affect autograft function and root diameters over time after the Ross operation compared to a tricuspid aortic valve?

Population

1,277 patients undergoing the Ross operation with intra-operatively documented aortic valve morphology from…

Comparison

Ross operation in the setting of a bicuspid… vs Ross operation in the setting of a tricuspid…

Design

Cohort

Follow-up

mean 5.7 ± 3.8 years

Authors

Thorsten Hanke
Thorsten HankeCross-Cutting Cardiology
ECEfstratios I. CharitosCardiac SurgeryUSUlrich StierleGoethe University Frankfurt

Discussion

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Implication

Supports Ross feasibility in BAV without excess regurgitation; leaves open long-term dilatation effects.

Structured PICO

Does the presence of a bicuspid aortic valve affect autograft function and root diameters over time after the Ross operation compared to a tricuspid aortic valve?

P
Population
1,277 patients (mean age 42.2 ± 15.3 years) undergoing the Ross operation with intra-operatively documented aortic valve morphology (bicuspid or tricuspid) from the German Ross Registry.
I
Intervention
Ross operation in the setting of a bicuspid aortic valve (BAV)
C
Comparator
Ross operation in the setting of a tricuspid aortic valve (TAV)
O
Outcome
Autograft function (neo-aortic regurgitation) and diameters (annulus, sinus, sinotubular junction) over timesurrogate

The Ross operation in patients with a bicuspid aortic valve is feasible and does not lead to increased neo-aortic regurgitation over time compared to tricuspid valves, despite slightly higher rates of root dilatation.

Cite This Study

Hanke et al. (2010) studied this question.

synapsesocial.com/papers/6a1e5fee25b49a996c68ccdehttps://doi.org/10.1016/j.ejcts.2010.01.064

Topics

Valvular heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abnormal Extracellular Matrix Protein Transport Associated With Increased Apoptosis of Vascular Smooth Muscle Cells in Marfan Syndrome and Bicuspid Aortic Valve Thoracic Aortic Aneurysm2003 · 352 citations
  2. 2Autograft Regurgitation and Aortic Root Dimensions After the Ross Procedure2007 · 62 citations
  3. 3Time Course of Aortic Valve Function and Root Dimensions After Subcoronary Ross Procedure for Bicuspid Versus Tricuspid Aortic Valve Disease2001 · 21 citations
  4. 4Ross Procedure at the Crossroads2009 · 43 citations
  5. 5Replacement of the Aortic Root with a Pulmonary Autograft in Children and Young Adults with Aortic-Valve Disease1994 · 290 citations