Why the study?
Is untreated essential hypertension associated with excessive arterial hypoxaemia compared to normotensive controls in men aged 35-65?
Is untreated essential hypertension associated with excessive arterial hypoxaemia compared to normotensive controls in men aged 35-65?
Mild to moderate essential hypertension in men is not associated with excessive nocturnal hypoxaemia indicative of sleep apnoea syndrome.
Answers are grounded in this paper and cite their sources.
No excess nocturnal hypoxaemia in untreated hypertensive men; leaves open whether severe hypertension or other groups merit targeted sleep evaluation.
Thirty men (aged 35-65) with untreated essential hypertension (BP greater than or equal to 140/90), confirmed by 24-h ambulatory monitoring, had overnight recordings of arterial oxygen saturation (SaO2) in their own homes. The overnight saturation records were compared with those from a group of 30 normotensive control subjects matched for age, height and weight. The groups did not exhibit significant differences in any of the following parameters of overnight oxygenation: median SaO2, lowest SaO2 or frequency of 3 or 4 per cent dips in SaO2. We conclude that essential hypertension is not associated with excessive arterial hypoxaemia such as might be due to a sleep apnoea syndrome.
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Warley et al. (1988) studied this question.
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