What question did this study set out to answer?

To measure the concentrations of volatile fatty acids and investigate tissue ketogenesis from butyrate within the fermentative digestive tracts of two kangaroo species and guinea-pigs.

March 1, 1970British Journal Of NutritionOpen Access

Concentrations and metabolism of volatile fatty acids in the fermentative organs of two species of kangaroo and the guinea-pig

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Authors

SHSusan HenningUniversity of North Carolina at Chapel Hill FHF.J.R. HirdThe University of Melbourne

Discussion

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Implication

Comparative laboratory analysis demonstrates high volatile fatty acid levels and mucosal ketogenesis from butyrate in kangaroos and guinea-pigs, highlighting shared fermentative metabolism.

Key Points

To measure the concentrations of volatile fatty acids and investigate tissue ketogenesis from butyrate within the fermentative digestive tracts of two kangaroo species and guinea-pigs.
Quantified concentrations of volatile fatty acids (acetate, propionate, n-butyrate, and branched-chain fatty acids) in contents taken from kangaroo and guinea-pig fermentative organs.
Incubated fermentative organ tissues in vitro, including guinea-pig caecal mucosa, upper colon, and kangaroo stomach, with 14C-labelled butyrate to monitor ketone body generation and oxidation to carbon dioxide.
Total volatile fatty acid concentrations in fermentative organ contents ranged from 50 to 140 mM across species, with acetic acid present at the highest levels, followed by propionic and n-butyric acids.
Wall tissue from fermentative organs metabolized butyrate primarily into acetoacetate without inhibition by acetate or propionate, with the highest ketogenic activity located in the caecal mucosa and upper colon.
Radiolabeled tracer experiments demonstrated that the proportion of butyrate oxidized to carbon dioxide was considerably lower than the proportion transformed into ketone bodies in both kangaroo stomachs and guinea-pig caeca.

Cite This Study

Henning et al. (1970) studied this question.

synapsesocial.com/papers/6a1e6d5c4e724749e768af59 https://doi.org/10.1079/bjn19700017

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Implication

Comparative laboratory analysis demonstrates high volatile fatty acid levels and mucosal ketogenesis from butyrate in kangaroos and guinea-pigs, highlighting shared fermentative metabolism.

Concentrations and metabolism of volatile fatty acids in the fermentative organs of two species of kangaroo and the guinea-pig

Discussion

Member takes

Implication

Key Points

Cite This Study

Concentrations and metabolism of volatile fatty acids in the fermentative organs of two species of kangaroo and the guinea-pig

Discussion

Member takes

Implication

Key Points

Cite This Study

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