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Synapse
November 1, 1994Circulation421 citationsOpen Access

Sudden cardiac death in heart failure. The role of abnormal repolarization.

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Population

Patients with congestive heart failure at risk for sudden cardiac death

Design

Review

Authors

GTGordon F. TomaselliDBD J BeuckelmannHCHugh Calkins

Discussion

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Overview

May underlie arrhythmic SCD risk in HF; leaves open targeted K+ channel modulation as a therapeutic strategy.

Structured PICO

P
Population
Patients with congestive heart failure at risk for sudden cardiac death
O
Outcome
Sudden cardiac death and arrhythmogenesis

This review highlights the potential role of altered repolarizing K+ channel expression in the pathogenesis of sudden cardiac death in heart failure patients.

Cite This Study

Tomaselli et al. (1994) studied this question.

synapsesocial.com/papers/6a1e6effd2dd52381c327fechttps://doi.org/10.1161/01.cir.90.5.2534
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