Peripheral giant cell granuloma (PGCG) is a reactive lesion typically confined to the gingiva or alveolar mucosa and is generally regarded as a soft tissue entity. Although superficial bone involvement has occasionally been described, extensive periodontal destruction is not consistently observed. This report describes a case of PGCG occurring in the maxillary anterior region in association with advanced periodontal bone loss. A 37‐year‐old male presented with a progressively enlarging, asymptomatic swelling between Teeth #11 and #12 of 3 months′ duration. Clinical examination revealed a pedunculated, purple‐red mass measuring approximately 14 × 11 mm. Periodontal assessment demonstrated Stage III, Grade C periodontitis with deep probing depths extending toward the apical third of the roots and Grade III mobility of the involved teeth. Radiographic evaluation showed advanced horizontal bone loss and a pronounced interdental periodontal defect. The lesion was completely excised with adequate margins, and due to extensive periodontal support loss, Teeth #11 and #12 were extracted during the same surgical procedure. Histopathological analysis confirmed the diagnosis of PGCG. Healing was uneventful, and no clinical signs of recurrence were observed at 1‐month follow‐up. This case highlights that PGCG may coexist with advanced periodontal destruction in natural dentition and emphasizes the importance of comprehensive periodontal evaluation and complete surgical excision to minimize recurrence risk.
Yildirim et al. (Thu,) studied this question.
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