Peripheral Gaint Cell Granuloma – A Case Report

The peripheral giant cell granuloma (PGCG) is an inammatory hyperplastic type of lesion, it is the most common type of oral giant cell lesion that probably involves a reactive response in the periosteum, periodontal ligament, and gingiva. The exact etiology is unknown, PGCG may occur due to response to local irritation. A 30 years old female patient reported with a chief complaint of swelling and loose teeth in the lower left front tooth region since more than a year. Intra-oral examination revealed the presence of a solitary, rm, smooth and sessile overgrowth. The superior surface of the lesion was bright red and ulcerated. The Orthopantomogram and intraoral periapical radiographs of the patient showed a well-demarcated oval radiolucency extending from mesial aspect of mandibular canine to distal aspect of mandibular rst premolar and bone resorption and severe bone loss around involved teeth. Excisional biopsy was performed under local anaesthesia and tissue was examined histopathologically. The lesion was diagnosed as PGCG after thorough clinical, radiologic and histopathologic examination.