Case series shows testosterone-lowering medication reduces problematic sexual behavior in males with intellectual disability, indicating a need for oversight.
Background Testosterone‐lowering medication (TLM) is used in severe cases of paraphilic disorders and problematic sexual behaviour, but its use in patients with intellectual disability is not well characterised. Method A nationwide survey identified five male patients with intellectual disability who had received TLM in specialised outpatient clinics. Results Four patients showed reduced problematic sexual behaviour during treatment; three relapsed after discontinuation. Adverse effects included osteoporosis, hypertension, depression and suppressed sexual development. Monitoring and access varied regionally. Conclusions TLM may be effective in selected patients with intellectual disability but requires careful monitoring and ethical oversight.
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Bentsen et al. (2026) studied this question.
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