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June 2, 2026Open Access

Nano-Formulation and Evaluation of Muco-Adhesive Buccal Patches of Metronidazole for Localized Oral Therapy

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Authors

MAMr. Ahemad Asadulla Pathan*, Mr. Pathan Muzakkir Ahmed, Dr. Shaik Gazi, Dr. MD Rayees Ahmad

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Implication

Randomized trial evaluates muco-adhesive buccal patches of metronidazole for oral infections, suggesting an effective treatment alternative.

Key Points

  • This research aims to develop muco-adhesive buccal patches of metronidazole for improved localized oral therapy.
  • Formulated buccal patches using chitosan as the polymeric carrier.
  • Utilized solvent-casting techniques for effective drug incorporation and buccal adhesion.
  • Conducted comprehensive characterization including physicochemical evaluation and in-vitro drug release.
  • Optimized patches showed increased residence time and controlled drug release.
  • Demonstrated adequate muco-adhesion and pronounced antimicrobial action against oral infections.

Cite This Study

Mr. Ahemad Asadulla Pathan*, Mr. Pathan Muzakkir Ahmed, Dr. Shaik Gazi, Dr. MD Rayees Ahmad (2026) studied this question.

synapsesocial.com/papers/6a1e734530b38c64201b6737https://doi.org/10.5281/zenodo.20470279
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A REVIEW ON FORMULATION AND EVALUATION OF BUCCAL PATCHES OF METRONIDAZOLE FOR THE TREATMENT OF PERIODONTITIS2026
  2. 2Formulation and evaluation of mucoadhesive microspheres of metronidazole2024 · 4 citations
  3. 3FORMULATION AND EVALUATION MUCOADHESIVE BUCCAL PATCHES OF TRIAMCINOLONE ACETONIDE AND LIDOCAINE HYDROCHLORIDE FOR EFFECTIVE TREATMENT OF MOUTH ULCERS2026
  4. 4FORMULATION AND EVALUATION MUCOADHESIVE BUCCAL PATCHES OF TRIAMCINOLONE ACETONIDE AND LIDOCAINE HYDROCHLORIDE FOR EFFECTIVE TREATMENT OF MOUTH ULCERS2026
  5. 5MUCOADHESIVE BUCCAL PATCHES: AN INTEGRATED PERSPECTIVE ON DRUG DELIVERY, MUCOADHESION, AND THERAPEUTIC APPLICATIONS2026