Why the study?
What factors are associated with ischemic stroke in patients with nonvalvular atrial fibrillation on therapeutic warfarin?
What factors are associated with ischemic stroke in patients with nonvalvular atrial fibrillation on therapeutic warfarin?
Patients with NVAF who have high clinical risk scores, prior stroke, or a smoking history remain at high risk for ischemic stroke even when optimally anticoagulated with warfarin.
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Residual stroke risk persists despite therapeutic warfarin in AF; hypothesis-generating for trials of intensified prevention.
Kim et al. (2015) studied this question.
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